Coagulation Factors
Product Description
Zeno Scientific delivers purified bovine and human coagulation enzymes, including high-activity thrombin and native prothrombin, specifically calibrated for clinical hemostasis diagnostic testing and in vitro diagnostic (IVD) kit manufacturing. Prepared through multi-step ion-exchange and affinity chromatography, our preparations provide consistent specific activity with minimal trace factor contamination.
Each lot is verified for functional fidelity across automated clotting-assay workflows, prothrombin time (PT), and activated partial thromboplastin time (aPTT) reagents. High batch-to-batch consistency safeguards formulation linearity and minimizes recalibration cycles for analytical research laboratories and diagnostic component formulators.
Our formulations demonstrate robust solubility across standard physiological buffers such as Tris-buffered saline and HEPES systems. Formulations ship via validated cold-chain express containers with dry ice or cooling packs. Recommended storage is at -20°C; aliquoting after initial reconstitution prevents destructive repeated freeze-thaw cycles and maintains sustained enzymatic potency.
Product Specification
| Parameter | Value |
|---|---|
| Source | Purified bovine/human plasma-derived and recombinant preparations |
| Specific Activity | ≥ 2,000 NIH Units/mg protein |
| Molecular Weight | ~36 kDa (α-thrombin) |
| Form | Lyophilized powder or liquid glycerol stock |
| Reconstitution | Sterile, enzyme-free water or Tris-buffered saline (TBS) |
| Formulation Buffer | Tris-HCl, NaCl, stabilizing proteins |
| Activity Verification | Validated via PT / aPTT clotting assay |
| Purity | ≥ 95–98% (SDS-PAGE / HPLC verified) |
| Storage Temperature | -20°C (long-term); 2–8°C (reconstituted, short-term) |
Ordering Information
Bulk and Custom Diagnostic OEM Formulations
Custom batch concentrations, carrier-free lyophilized formats, and annual reserve agreements are available for IVD manufacturing partners.